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The Importance of Preserving Residual Beta-Cell Function in T1D
Maintaining residual beta-cell function in T1D improves glycemic control, reduces complications, and impacts care and outcomes in people with T1D.
Learning Objectives
- Understand the definition and measurement of residual beta-cell function (C-peptide levels) in T1D
- Recognize the benefits of preserved beta-cell function on glycemic outcomes and insulin requirements
- Appreciate the role of residual beta-cell function in reducing long-term complications and severe hypoglycemia, especially in pediatric populations
Summary
This video examines the profound impact of residual beta-cell function, measured by C-peptide levels, on T1D management. It highlights the significant benefits of preserving beta-cell function, including lower glycemic variability, improved glycemic outcomes, and reduced insulin requirements. Maintaining residual beta cell function also decreases the risk of hypoglycemia and long-term complications. The discussion specifically addresses the pediatric population, in which higher C-peptide levels enable easier achievement of metabolic objectives with lower insulin needs and a critical reduction in severe hypoglycemia. This underscores its importance as a key therapeutic objective in T1D.
MAT-GLB-2506947 - 1.0 - 12/2025
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