The BR1DGE Podcast - Episode 2: Screening for T1D in the Real World

Learning Objectives

• Understand both the history and current role of islet autoantibody screening in identifying early-stage type 1 diabetes and reducing the risk of DKA at diagnosis 
• Evaluate the challenges to implementing screening programs for type 1 diabetes 
• Explore the potential of population-based screening programmes for improving outcomes for individuals at risk of type 1 diabetes 

Summary

In this second podcast episode, Prof. Ezio Bonifacio discusses the evolution and impact of T1D screening. He traces the development of autoantibody testing from early research to accessible commercial assays, emphasizing its role in identifying early-stage T1D. Prof. Bonifacio advocates for universal childhood screening, highlighting its potential to prevent severe complications like diabetic ketoacidosis and allow for proactive management. He addresses key challenges such as ensuring acceptance, implementing repeated screening, and the critical need for confirmatory testing. Finally, he discusses a future vision of structured screening for all children and adolescents, combined with effective monitoring and treatment with therapies that delay T1D progression.  

Listen on Spotify

MAT-GLB-2500704-1.0 – 05/2025