- Resource
- BR1DGE
- Pathophysiology
- Staging
- Video
The BR1DGE Podcast - Episode 4: T1D Diagnosis in Adults
Partha Kar talks to Alice Cheng about how to correctly diagnose adult-onset type 1 diabetes, including the role of clinical tools such as the AABBCC criteria and IAb testing.
Learning Objectives
- Appreciate that more than half of diagnoses of type 1 diabetes occur in adulthood
- Understand how to apply the AABBCC criteria and other tools, including testing for IAbs, to differentiate between type 1 and type 2 diabetes in adults
- Understand the importance of maintaining a high index of suspicion for T1D in adults
Summary
Professor Alice Cheng discusses the significant challenge of T1D misdiagnosis in adults. Adult-onset T1D accounts for over 50% of new T1D cases, and often presents atypically, leading to inappropriate management and increased disease burden, including DKA. Cheng discusses the "AABBCC" framework (Age, Autoimmunity, Body habitus, Background, Control, Comorbidities), and the role of autoantibody screening and C-peptide in differential diagnosis. She highlights how accurate staging and diagnosis can open avenues for appropriate therapy and improved patient outcomes. The future promises enhanced diagnostic tools, including AI and genetic markers, that can help unravel the underlying pathophysiology and enable tailored monitoring.
MAT-GLB-2500706-1.0 – 09/2025
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Insights and Learnings from T1D Screening Programs
A short video from EASD 2025 exploring learnings from implementation of population-level T1D screening programs .
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Key Insights from T1D Screening Programs Highlight the Benefits of Early Detection
A short video of Professor Albanese O’Neil describing the benefits of early detection of T1D as discovered through early detection screening programs.
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Current and Future Management Options for T1D
A short video of Professor Colin Dayan describing the current and potential future therapeutic options for managing T1D.