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BR1DGE Talk Show: The Impact of Late Diagnosis

Explore how diabetic ketoacidosis (DKA) affects people with T1D and their families, and learn why early detection through autoantibody screening can prevent this crisis. 

Learning Objectives

  • Understand the pathophysiology and life-threatening consequences of diabetic ketoacidosis (DKA) in type 1 diabetes diagnosis
  • Recognize how early detection through islet autoantibody screening can reduce DKA rates to less than 5%
  • Apply knowledge of screening strategies to support families through early-stage diagnosis, improving long-term glycemic control and psychological well-being 

Summary

In this compelling panel discussion, pediatric endocrinologist Kimber Simmons, and researcher Jurgen Vercauteren join host Vivienne Parry to examine the devastating impact of diabetic ketoacidosis (DKA) at diagnosis. They explore how 20–50% of new type 1 diabetes cases present with DKA – a life-threatening emergency requiring ICU admission with lasting effects on cognitive function, glycemic control, and psychological well-being. They highlight evidence that early T1D detection through islet autoantibody screening can reduce DKA rates to under 5%, improving outcomes for people diagnosed with T1D, as well as providing families with crucial preparation time and access to clinical trials. 

MAT-GLB-2507508 - 1.0 - 02/2026