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BR1DGE Talk Show: The Impact of Late Diagnosis

Explore how diabetic ketoacidosis (DKA) affects patients and their families, and learn why early detection through autoantibody screening can prevent this crisis. 

Learning Objectives

  • Understand the pathophysiology and life-threatening consequences of diabetic ketoacidosis (DKA) in type 1 diabetes diagnosis
  • Recognize how early detection through islet autoantibody screening can reduce DKA rates to less than 5%
  • Apply knowledge of screening strategies to support families through early-stage diagnosis, improving long-term glycemic control and psychological well-being 

Summary

In this compelling panel discussion, pediatric endocrinologist Kimber Simmons, and type 1 diabetes researcher Jurgen Vercauteren join host Vivienne Parry to examine the devastating impact of diabetic ketoacidosis (DKA) at diagnosis. They explore how 20–50% of new type 1 diabetes cases present with DKA – a life-threatening emergency requiring ICU admission with lasting effects on cognitive function, glycemic control, and psychological well-being. They highlight evidence that early T1D detection through islet autoantibody screening can reduce DKA rates to under 5%, improving outcomes for people diagnosed with T1D, as well as providing families with crucial preparation time and access to clinical trials. 

Jurgen Vercauteren Kimber Simmons Vivienne Parry

MAT-GLB-2507508 - 1.0 - 02/2026