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An Overview of Islet Autoantibody Tests

Dr Daniel Agardh discusses the multiple technologies now available for detecting islet autoantibodies associated with type 1 diabetes  

Learning Objectives

  • Provide an overview of current technologies used in detecting autoantibodies in T1D 
  • Highlight differences in each technology and how these technologies are implemented across different countries/projects 

Summary

Multiple technologies are now available for detecting type 1 diabetes islet autoantibodies including RBA, ECL, LIPS, ELISA, and ADAP.

Screening programs worldwide use different combinations of technologies and choice of method varies by country and program, goals and availability. Some use a single assay, others have the ability to combine methods for confirmation. These differences reflect local infrastructure, resources, and efforts to ensure accurate detection of islet autoantibodies.

MAT-GLB-2501742-1.0 - 05/2025