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Module 2: Early Detection of Autoimmune Type 1 Diabetes

This module focuses on methods and strategies for identifying T1D in its presymptomatic stages, emphasizing the benefits of early diagnosis

 

 

Chapter 2.1: The Importance of Early Screening

This sub-chapter will highlight why early identification of T1D is crucial for better patient outcomes and prevention of severe complications.

Learning Objective

  • Explain why early detection of T1D remains essential despite recent advances in treatment.

 

 

Chapter 2.2: Key Markers: Islet Autoantibodies (IAbs) and Genetic Risk

 

This sub-chapter will describe the use of islet autoantibodies as biological indicators used to diagnose T1D.

Learning Objectives

 

  • Highlight that autoantibody screening can identify people with type 1 diabetes
  • To guide the viewer through the different options available for blood sample collection and analysis

Chapter 2.3: Screening Programs in Type 1 Diabetes

 

This sub-chapter will cover the current status of T1D screening globally, including example screening programs and the insights taken from them.

Learning Objectives

  • Understand both the history and current role of islet autoantibody screening in identifying early-stage T1D and reducing the risk of DKA at diagnosis 
  • Evaluate the challenges to implementing screening programs for T1D
  • Explore the potential of population-based screening programs for improving outcomes for individuals at risk of T1D

Learning Objectives

  • Discuss the key criteria and requirements needed to set up a real-world T1D screening program  
  • Highlight potential strategies that can be implemented in driving and retaining patient engagement 

Chapter 2.4: Adult-onset Type 1 Diabetes

 

This sub-chapter will cover the tools and approaches available to detect type 1 diabetes in adult populations.

Learning Objectives

  • Appreciate that more than half of diagnoses of T1D occur in adulthood
  • Understand how to apply the AABBCC criteria and other tools, including testing for IAbs, to differentiate between type 1 and type 2 diabetes in adults
  • Understand the importance of maintaining a high index of suspicion for T1D in adults 

Learning Objectives
 

  • Highlight the prevalence and differentiating clinical characteristics of adult-onset T1D versus T2D
  • Educate on the burden and misclassification of adult-onset T1D

Chapter 2.5: The Practicalities of Setting up an IAb Screening Program

 

This sub-chapter will cover practicalities of T1D screening globally, including guidance on how to set up an IAb screening program.

Learning Objectives


The T1D Early Detection Toolkit is a collaboration with external experts and organizations to create a clear, practical resource for healthcare professionals who wish to start type 1 diabetes screening programs.

 

This toolkit aims to:

  • Summarize the latest scientific knowledge and real-world experience in an accessible, ​step-by-step format​ 
  • Provide clinicians with straightforward guidance that can be easily adapted according to local resources, healthcare structures, and clinical pathways 

 

Download 

Early detection toolkit

Congratulations on completing BR1DGE Module 2: Early Detection of Autoimmune Type 1 Diabetes!

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