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BR1DGE Talk Show: Timing Matters - The Evolving Story of Type 1 Diabetes

Explore how decades of advancements in biomarkers, genetics, and staging frameworks have culminated in our ability to “see” T1D before symptoms emerge.

Learning Objectives

  • Understand the autoimmune basis of type 1 diabetes and the role of autoantibodies  
  • Describe the early stages of type 1 diabetes and the criteria used for staging  
  • Explain the benefits of population screening for early detection of type 1 diabetes, including the reduction of diabetic ketoacidosis (DKA)  

Summary

In this episode of the BR1DGE Talk Show, host Vivienne Parry joins experts Jacques Beltrand and Luis Castaño to discuss the paradigm shift in our understanding of type 1 diabetes. They explore the autoimmune nature of T1D, which can be detected years before clinical symptoms appear by screening for autoantibodies. The experts review data from population screening studies, which show a dramatic reduction in life-threatening diabetic ketoacidosis (DKA) at diagnosis and open a crucial window to potentially delay the need for insulin. 

MAT-GLB-2507507 - 1.0 - 03/2026