This symposium explores who should be screened for early-stage type 1 diabetes and how findings translate into practical staging, monitoring, and care pathways. It also reviews real-world evidence on disease-modifying therapies and examines C-peptide's role as a biomarker for tracking beta-cell preservation and guiding treatment decisions.
The Early-stage T1D Care Pathway: Practical and Real-world Experience
Madrid Room, North Wing, Level 2, Allianz MiCo, Milan, Italy
Agenda
18:00–18:05 - Welcome and Introduction (Chantal Mathieu - Chair)
18:05–18:25 - A Hidden T1D Population: The Rationale for Screening Young Adults in Clinical Practice (Jeremy Pettus)
18:25–18:35 - From Detection to Care: Considerations for Real-world Early Detection Pathway Design in Adult Practices (Chantal Mathieu)
18:35–18:50 - Beta-cell Preservation in Practice: Real-world Insights and the Role of C-peptide (Marwa Tuffaha)
18:50–19:00 - Panel Discussion (All faculty)
Meeting Objectives
Examine the evidence base for targeted screening of young adults with dysglycemia and individuals with autoimmune conditions as priority populations for early-stage autoimmune type 1 diabetes (T1D) detection
Discuss practical approaches to staging, monitoring, and care pathway design for early-stage T1D in adult clinical practice
Explore the emerging real-world evidence on disease-modifying therapies in T1D
Appraise the clinical utility of C-peptide as a prospective biomarker of beta-cell preservation and treatment efficacy, as well as its implications for management on disease-modifying therapies
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